What is the RRF and how to calculate RRF
What is the RRF and how to calculate RRF
Replies to this topic (3)
RRF elaborates Relative Response Factory.
It refers to the ratio of slope of known impurity to the slope of API
If you wants to know the RRF of an impurity, you should first need to perform Linearity to the impurity and API.
From the Linearity, you will get slope for the impurity and API
Then , divide slope of impurity with slope of API.
The result is RRF of particular impurity .
RRF is Relative Response Factor. Spelled wrong in the above answer
RRF-Relative response factor.if RRF value of known impurities.perform the linearity of Analyte ( std) and impurities.take the slope values and calculate. RRF= Impurity slope/ Analyte slope . These RRF value should apply method precision for Rs sample calculation and cross check RRF values with monograph of API and FP methods.