Naproxen-Detailed drug information
Description
Detail drug information on Naproxen
Class: Analgesics, musculoskeletal agent
Mechanism of action: Naproxen is a propionic acid derivative NSAID with analgesic, anti-inflammatory, and antipyretic activities. The mechanism of action is unknown but involves inhibition of cyclooxygenase (COX-1 and COX-2), which leads to reduced prostaglandin synthesis.
Pharmacokinetics:
Absorption
Oral, tablet: time to peak concentration, 2 h to 4 h
Oral, suspension: time to peak concentration, 1 h to 4 h
Oral, delayed release tablet: time to peak concentration, 4 h to 6 h (2 h to 12 h)
Bioavailability: 95
