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Abstract:- Indole Containing compounds have shown a broad spectrum of biological effects including anti-cancer, anti-viral, anti-bacterial and anti-inflammatory.. The product 3-(7-Nitrobenzylidene)indolin-2-one synthesized by using nitrobenzaldehyde and Oxindole in presence of Na2CO3. These findings revealed that 3-(7-Nitrobenzylidene)indolin-2- one retains a significant anti-fungal activity against Staphylococcus Aureus And Serratia Marcescens, an important pathogen

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